Table 1.
Demographic Characteristics and Basic Clinical Information
| PD whole (n=49) | HC whole (n=38) | T or χ2 value | P value | |
|---|---|---|---|---|
| Age (years) | 71.71±7.49 | 70.34±7.57 | 0.8438 | 0.2006 |
| Sex (male) | 46.94% | 47.37% | 0.0020 | 0.4843 |
| Smoking | 24.49% | 23.68% | 0.0080 | 0.4658 |
| Drinking | 16.33% | 18.42% | 0.0660 | 0.4002 |
| Disease duration (years) |
4.80±3.09 | — | — | — |
| LEDD(mg) | 569.74±240.97 | — | — | — |
| Respiratory rate | 18.84±1.33 | 18.55±1.29 | 1.0030 | 0.1595 |
| Pulse rate | 77.63±9.69 | 78.71±8.37 | 0.5458 | 0.2933 |
| Systolic blood pressure | 125.67±8.30 | 125.34±7.80 | 0.1896 | 0.4250 |
| Diastolic blood pressure | 71.06±8.23 | 70.58±7.90 | 0.2760 | 0.3916 |
| UPDRS II | 14.00±6.67 | — | — | — |
| UPDRS III | 25.98±10.15 | — | — | — |
| H-Y stage | 2.51±1.13 | — | — | — |
| MoCA | 25.02±2.93 | 27.47±1.54 | 4.6770 | <0.0001*** |
| PDSS-2 | 14.96±3.86 | 8.53±3.62 | 7.9230 | <0.0001*** |
| ESS | 5.59±4.20 | 5.03±2.64 | 0.7257 | 0.2350 |
| RBDSQ | 4.10±1.93 | 1.55±1.35 | 6.9340 | <0.0001*** |
| HAMA | 11.22±4.28 | 6.68±4.13 | 4.9860 | <0.0001*** |
| HAMD-17 | 12.45±5.53 | 7.16±5.01 | 4.6090 | <0.0001*** |
Notes: ***indicates p value < 0.001.
Abbreviations: PD: Parkinson’s disease, HC: healthy controls, LEDD: levodopa equivalent daily dose, UPDRS: unified Parkinson’s disease rating scale, H-Y: Hoehn-Yahr, MoCA: Montreal cognitive assessment, PDSS: Parkinson’s disease sleep scale, ESS: Epworth sleepiness scale, RBDSQ: REM sleep behavior disorder screening questionnaire, HAMA: Hamilton anxiety rating scale, HAMD: Hamilton depression rating scale.