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. 2024 Sep 29;14:22579. doi: 10.1038/s41598-024-73112-5

Table 3.

Univariate and multivariate logistic regression of microcirculatory changes and an elevated lactate-albumin ratio on PICU admission.

Parameters Univariate analysis Multivariate analysis
OR (95% CI) p value aOR (95% CI) p value*
Capillary density 4–6 microns 1.03 (1.01–1.06) < 0.01 1.03 (1-01-1.05) < 0.01
Capillary density 10–20 microns 1.01 (1.00-1.01) 0.06 1.01 (0.99–1.02) 0.08
Absolute vascular flow 1.25 (1.10–1.49) < 0.01 1.31 (1.08–1.58) < 0.01
MVHS 0.97 (0.84–1.13) 0.77 0.98 (0.84–1.14) 0.82
PBR 1.25 (0.63–2.48) 0.52 1.20 (0.57–2.51) 0.86
PBR flow corrected 1.11 (0.55–2.22) 0.77 1.13 (0.53–2.35) 0.74
Worst PBR 1.28 (0.79–2.09) 0.31 1.18 (0.72–1.94) 0.51

MVHS: MicroVascular Health Score (the ratio between the PBR and relative vascular flow). PBR: perfused boundary region. CI: confidence interval. OR odds ratio. The adjusted odds ratio (aOR) was calculated for confounding variables (PIM-2, age and vasoactive index score). A lactate-albumin ratio greater than 0.5 was considered elevated. *Logistic regression using the forward method and omnibus test.