TABLE 3.
Univariate and multivariate linear regression analyses of factors associated with 17‐item Hamilton Rating Scale for Depression (HAMD‐17) score in obstructive sleep apnea (OSA) patients.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Characteristics | Beta Coefficient | p | 95% CI | Standardized coefficient | p | VIF |
| Demographic and clinical characteristics | ||||||
| Age | .043 | .736 | −.219 to .301 | |||
| Gender | .042 | .738 | −.219 to .317 | |||
| Education | −.202 | .106 | −.443 to .052 | |||
| BMI | −.21 | .093 | −.477 to .079 | |||
| Polysomnographic data | ||||||
| Sleep efficiency, % | −.242 | .052 | −.468 to .061 | |||
| Sleep stage, %TST | ||||||
| REM | .166 | .185 | −.081 to .429 | |||
| N1 | −.32 | .009 | −.555 to −.072 | −.363 | .003 | |
| N2 | .171 | .174 | −.063 to .408 | |||
| N3 | .189 | .132 | −.008 to .133 | |||
| AHI, events/h | −.267 | .031 | −.478 to −.029 | |||
| Mean SpO2, % | .212 | .09 | −.042 to .433 | |||
| Lowest SpO2, % | .289 | .02 | .013–.52 | |||
| fNIRS data | ||||||
| VFT performance | −.085 | .503 | −.353 to .168 | |||
| Oxy‐Hb changes in Channel 13 | −.215 | .085 | −.432 to .048 | |||
| Oxy‐Hb changes in Channel 43 | −.319 | .01 | −.526 to −.074 | |||
Note: Bold font indicates variables with statistically significant differences between clusters (p < .05).
Abbreviations: AHI, apnoea‐hypopnoea index; BMI, body mass index; fNIRS, functional near‐infrared spectroscopy; HAMD‐17, 17‐item Hamilton Rating Scale for Depression; Lowest SpO2, Lowest oxygen saturation; Mean SpO2, Mean oxygen saturation; N1, non‐REM (NREM) Stage 1; N2, non‐REM (NREM) Stage 2; N3, non‐REM (NREM) Stage 3; Oxy‐Hb, oxy‐hemoglobin; REM, rapid eye movement; TST, total sleep time; VFT, verbal fluency task; VIF, variance inflation factor.