Table 1.

Timeline summarizing significant events and key research milestones that led to the development and validation of the Next Generation Biosecurity concept.

Years	Milestone
2000	PRRSV-naïve breeding stock and semen become commercially available.
2001	Area Spread of PRRSV is described.
2002–2004	Mechanical risks (contaminated transport, clothing/footwear, and incoming supplies) for the spread of PRRSV are identified.
2005–2007	Protocols of transport sanitation, personnel entry, and supply entry are validated.
2007–2010	Aerosol transmission and long-distance airborne transport of PRRSV are identified.
2009–2012	Air filtration for PRRSV prevention is validated.
2014–2023	The risk of contaminated feed for the transmission of viruses of veterinary significance is discovered.
2014–2022	Feed biosecurity protocols (additives, storage) are developed.
2021–2024	Next Generation Biosecurity concept developed and tested.