FIGURE 5.

Oleuropein increases the proteasome activity in N2a cells expressing the truncated HttQP72-GFP mHtt protein. Oleuropein increases the proteasome activity in N2a cells expressing the truncated HttQP72-GFP mHtt protein. The chymotrypsin-like activity (A), caspase-like activity (B), and trypsin-like activity (C) were examined in N2a cells expressing wild-type or the truncated mHtt in the absence or presence of 5 μg/ml oleuropein treatment at the indicated concentration for 24 h. Data from three independent experiments are presented as mean normalized units ± SEM. Data showing a significant difference (p < 0.05) is labeled with one asterisk (*). N.S., not significant.