Table 1.
Characteristics of studies on association between NAFLD and CVDs.
| Authors | Region | Total cases | Diagnosed method | Outcomes | OR (95% CI) | HR (95% CI) | RR | |
| NAFLD/MAFLD | CVDs | |||||||
| Agaç MT et al. [36] | USA | 3976 | CT | CT | CAC | 1.37 (1.11–1.68) | - | - |
| Fudim M et al. [37] | USA | 870,535 | Database record | ICD-9/10 | HF | - | 1.23 (1.19–1.29) | 1.30 |
| Gummesson A et al. [38] | Sweden | 1015 | CT | Ultrasound | CAC | 1.77 (1.07–2.94) | - | - |
| Guo Y et al. [39] | China | 11,444 | Multiple criteria | ICD-10 | CVDs | - | 1.37 (1.20–1.56) | 2.04 |
| Kang MK et al. [40] | Korea | 772 | Ultrasound | CT | CA | 1.48 (1.05–2.08) | - | 1.49 |
| Lee H et al. [41] | Korea | 8,962,813 | FLI | ICD-10 | CVDs | - | NAFLD: 1.09 (1.03–1.15) | 2.29 |
| MAFLD: 1.43 (1.41–1.45) | ||||||||
| Lee SB et al. [7] | Korea | 5121 | Ultrasound | CT | CA | 1.18 (1.03–1.35) | - | 1.32 |
| Roh JH et al. [42] | Korea | 308,578 | FLI | ICD-10 | HF | - | 2.71 (2.380–3.085) | 1.62 |
| Simon TG et al. [43] | Sweden | 56,939 | Biopsy | ICD-10 | MACEs | - | 1.63 (1.56–1.70) | - |
| VanWagner LB et al. [44] | USA | 2424 | CT | CT | CAC | 1.33 (1.001–1.82) | - | 1.46 |
| Wong VW et al. [45] | China | 612 | Ultrasound | CC | CAD | 2.31 (1.46–3.64) | - | 1.32 |
| Yu MM et al. [46] | China | 1683 | CT | CT | MACEs | - | 1.63 (1.28–2.06) | 1.99 |
| Chung GE et al. [47] | Korea | 3300 | Ultrasound | Echocardiography | LV diastolic dysfunction | 1.29 (1.07–1.60) | - | - |
NAFLD, non-alcoholic fatty liver disease; MAFLD, metabolic associated fatty liver disease; CVDs, cardiovascular diseases; HF, heart failure; MACEs, major adverse cardiovascular events; FLI, fatty liver index; CT, computed tomography; CA, coronary atherosclerotic; CAC, coronary artery calcium; CAD, coronary artery disease; ICD, the International Statistical Classification of Diseases and Related Health Problems; CC, cardiac catheterization; LV, left ventricular; OR, odds ratio; HR, hazard ratio; CI, confidence interval; RR, relative risk (RR was calculated by the extracted data from the research).