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. 2024 Sep 28;56(1):2409352. doi: 10.1080/07853890.2024.2409352

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 6. — Single-cell sequencing results. (A) t-distributed Stochastic Neighbor Embedding (t-SNE) visualization of the 12 samples. (B) t-SNE plots comparing normal and IPF samples. (C) t-SNE representation of the 28 cell clusters. (D) Cell types were delineated based on marker gene profiles. (E) Heat map displaying the top 5 marker genes across 8 cell types. (F) Comparative analysis of 5 hub genes between IPF and control groups. (G) Feature plots illustrating the expression of the 5 hub genes across 8 cell types. (H) Differential comparison of the 5 hub genes among the 8 cell types, highlighting the variance in gene expression patterns.