. Author manuscript; available in PMC: 2024 Sep 30.

Published in final edited form as: Vet Pathol. 2021 Nov 18;59(4):578–585. doi: 10.1177/03009858211058837

Table 1.

Comparison of select structural, cellular, and expression parameters between human and mouse airways related to airway mucus.

Airway parameter	Human trachea	Human distal airways	Mouse trachea
Caliber (mm)^74,80,85	15–20	0.5–1.0	~1.5
Submucosal glands (μL cm⁻²)^14,70	25–40	Zero	Zero to rare
Surface epithelium height (μm)^87,94	50–100	15	11–14
Club cells (% of surface epithelium)⁸¹	0	11–41	>50
Goblet cells (% of surface epithelium)^81,87	9	0–2	<1
ATP12A expression¹⁰¹	High	Nominal to absent	Nominal to absent