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. 2024 Sep 30;30(10):e70071. doi: 10.1111/srt.70071

FIGURE 1.

FIGURE 1

Effect of the cold plasma on psoriasis improvement in psoriasis cell lines from HaCaT cell. (A) Cold plasma device (RE:DERM PLASM, JNL, Korea). (B) HaCaT cell viability was measured after 0, 10, 20, 30, 60, 120, 180, and 240 s of cold plasma treatment and 24 h post‐treatment by using WST‐8 assay. (C) HaCaT cell viability was measured after 0, 10, 20, 30, 60, 120, 180, and 240 s of cold plasma treatment and 0, 4‐, 8‐, 12‐, and 24‐h post‐treatment by using WST‐8 assay. (D) The relative expression level of inflammatory cytokines related with psoriasis mRNA level after cytokine mixture treatment for 0, 0.5, 1, 2, 6, and 12 h. (E) The relative expression level of inflammatory cytokines related with psoriasis mRNA level after cytokine mixture treatment, cold plasma was applied for 0, 2, 4, 6, 8, and 10 min. (F–H) The expression level of MAPK pathway, cell cycle, psoriasis relative marker after cytokine mixture treatment for 0, 0.5, 1, 2, 6, and 12 h. The values represent the mean ± standard deviation. Significant values are indicated as *p < 0.05, **p < 0.01, ***p < 0.001, **** p < 0.0001 versus Normal.