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. 2024 Aug 20;4(5):e448. doi: 10.1002/ski2.448

TABLE 1.

Newer skin therapeutics and their protective effects on skin.

New skin therapeutics Mechanism of action References
Urea
  • Enhances skin hydration by drawing moisture to the skin's outer layer and augmenting its water‐retention capacity

12
Filaggrin
  • Involved in the formation of protective skin barrier

13
Natural oils (e.g. argan, coconut and jojoba)
  • Enhances skin hydration

  • Anti‐inflammatory

14
Botanical extracts (e.g. chamomile, aloe vera and green tea)
  • Antioxidant

  • Anti‐inflammatory

14
Ceramides
  • Forms a protective barrier against moisture loss

15, 16
Vitamin E
  • Fat‐soluble vitamins with potent antioxidant activities

17
Squalene
  • An excellent moisturiser

  • Keeps skin hydrated and supple

18