TABLE 2.
Logistic regression analysis of the relationship between inflammation/nutrition-based indicators and the prevalence of Parkinson’s disease among adults in NHANES 1999–2018.
| Crude | Model 1 | Model 2 | ||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| NAR | 1.389(1.055, 1.828) | 0.019 | 1.345 (1.016, 1.780) | 0.039 | 1.126 (0.837, 1.515) | 0.429 |
| PNI | 0.534 (0.401, 0.712) | < 0.001 | 0.689 (0.513, 0.925) | 0.014 | 0.702 (0.515, 0.957) | 0.026 |
| MAR | 1.036 (0.787, 1.364) | 0.800 | 0.972 (0.737, 1.281) | 0.838 | 0.853 (0.640, 1.137) | 0.276 |
| RAR | 2.667 (1.918, 3.709) | < 0.001 | 2.245 (1.594, 3.162) | < 0.001 | 1.872 (1.320, 2.655) | < 0.001 |
| HALP score | 0.723 (0.545, 0.959) | 0.025 | 0.860 (0.651, 1.138) | 0.289 | 0.826 (0.617, 1.106) | 0.198 |
| ALI | 1.577 (1.173, 2.122) | 0.003 | 1.438 (1.071, 1.932) | 0.016 | 1.300 (0.962, 1.758) | 0.088 |
| GNRI | 1.062 (0.807, 1.397) | 0.665 | 1.144 (0.858, 1.525) | 0.358 | 1.088 (0.814, 1.455) | 0.566 |
| CONUT score | 1.233 (0.949, 1.601) | 0.117 | 1.155 (0.883, 1.510) | 0.291 | 1.050 (0.806, 1.369) | 0.715 |
NAR, neutrophil-albumin ratio; PNI, prognostic nutritional index; MAR, monocyte-albumin ratio; RAR, red cell distribution width-albumin ratio; HALP, hemoglobin, albumin, lymphocyte, and platelet; ALI, advanced lung cancer inflammation index; GNRI, geriatric nutrition risk index; CONUT, controlling nutritional status; Inflammation/nutrition-based indicators were classified into two groups based on the median, with participants below the median used as the reference in the regression model. Model 1: Adjusted for age (20–39, 40–59, or ≥ 60 years), sex (male or female), and race/ethnicity (non-Hispanic White, non-Hispanic Black or other race); Model 2: Model 1 + marital status (married/living with partner, or single/divorced/widowed), education level (below high school, high school, or above high school), family PIR ( ≤ 1.0, 1.1–3.0, or > 3.0), drinking status (nondrinker, former drinker, or current drinker), smoking status (never smoker, former smoker, or current smoker, physical activity (inactive, insufficiently active, or active), HEI (in quartiles), and CCI (continous).