TABLE 3.
COX regression analysis of the relationship between inflammation/nutrition-based indicators and all-cause mortality among adults in NHANES 1999–2018.
| Crude | Model 1 | Model 2 | ||||
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| NAR | 1.482 (1.376, 1.596) | < 0.001 | 1.534 (1.434, 1.642) | < 0.001 | 1.245 (1.163, 1.333) | < 0.001 |
| PNI | 0.463 (0.435, 0.493) | < 0.001 | 0.738 (0.692, 0.787) | < 0.001 | 0.723 (0.674, 0.775) | < 0.001 |
| MAR | 1.796 (1.660, 1.942) | < 0.001 | 1.495 (1.387, 1.610) | < 0.001 | 1.273 (1.184, 1.369) | < 0.001 |
| RAR | 2.846 (2.670, 3.033) | < 0.001 | 1.930 (1.806, 2.063) | < 0.001 | 1.653 (1.549, 1.765) | < 0.001 |
| HALP score | 0.774 (0.717, 0.835) | < 0.001 | 0.899 (0.837, 0.965) | 0.003 | 0.841 (0.777, 0.910) | < 0.001 |
| ALI | 1.499 (1.402, 1.601) | < 0.001 | 1.275 (1.198, 1.358) | < 0.001 | 1.165 (1.092, 1.244) | < 0.001 |
| GNRI | 0.838 (0.785, 0.894) | < 0.001 | 0.818 (0.771, 0.868) | < 0.001 | 0.753 (0.710, 0.798) | < 0.001 |
| CONUT score | 1.396 (1.299, 1.500) | < 0.001 | 1.343 (1.255, 1.438) | < 0.001 | 1.312 (1.226, 1.403) | < 0.001 |
NAR, neutrophil-albumin ratio; PNI, prognostic nutritional index; MAR, monocyte-albumin ratio; RAR, red cell distribution width-albumin ratio; HALP, hemoglobin, albumin, lymphocyte, and platelet; ALI, advanced lung cancer inflammation index; GNRI, geriatric nutrition risk index; CONUT, controlling nutritional status. Inflammation/nutrition-based indicators were classified into two groups based on the median, with participants below the median used as the reference in the regression model. Model 1: Adjusted for age (20–39, 40–59, or ≥ 60 years), sex (male or female), and race/ethnicity (non-Hispanic White, non-Hispanic Black or other race); Model 2: Model 1 + marital status (married/living with partner, or single/divorced/widowed), education level (below high school, high school, or above high school), family PIR ( ≤ 1.0, 1.1–3.0, or > 3.0), drinking status (nondrinker, former drinker, or current drinker), smoking status (never smoker, former smoker, or current smoker), physical activity (inactive, insufficiently active, or active), HEI (in quartiles), and CCI (continous).