Fig. 2. Spectral patterns are similar across basal ganglia nuclei in dystonia patients.

A When averaged across hemispheres of all subjects, similar spectral patterns are observed with spectral peaks in the low-frequency (upper row) and beta band (lower row) in the striatum (STR, left column), GPi (mid column) and GPe (right column). Averaged power spectra across hemispheres and patients are colored (STR=purple, GPi=green, GPe=blue), while individual power spectra of each hemisphere are plotted in grey. For visualization purposes, power spectra are flattened and aligned to the individual peak frequency. No significant difference in power spectral density at peak frequency is seen across basal ganglia nuclei. B Similarly, peak frequencies in the respective frequency bands (low frequency and beta band) in the 19 hemispheres per structure did not significantly differ across basal ganglia nuclei and were distributed across the low frequency (upper row) and beta band (lower row) as validated by permutation tests and FDR-corrected for multiple comparisons. n.s. not significant. In box plots, the whiskers indicate minimal and maximal values per hemisphere, the central marks indicate the median and edges the 25th and 75th percentiles of the distribution. A.u. arbitrary units.