Table 1.
EPC phenotype | Status | Positive Phenotyping markers | Negative phenotyping markers | Note | |
---|---|---|---|---|---|
nhEPC | ECFCs | Ex vivo | CD31/CD34/CD144 | CD45/CD133/ CD14/CD41a | Late-outgrowth EPC |
hEPC | CD34+ or CD133+ | In vivo | CD34/CD133 /CD45 | CD14 | Immature hEPC subset |
Cultured EPCs | Ex vivo | CD31/CD45 | CD41a/CD235a | Early-outgrowth EPC, including MACs | |
Monocytic EPCs | In vivo | CD14/CD45 | CD133/CD34-/dim | Circulating monocyte subset |
EPCs Endothelial progenitor cells, ECFCs Endothelial colony-forming cells, hEPCs hematopoietic lineage cell-derived cells, nhEPCs non-hEPC, MACs myeloid angiogenic cells