Table 1.
Baseline characteristics of 99,877 participants by autosomal mCAs status.
| Autosomal mCAs carriers | Non-carriers | P | |
|---|---|---|---|
| No. of participants | 2612 | 97,265 | – |
| Women | 1407 (53.9) | 55,765 (57.3) | 0.012 |
| Age group | |||
| ≤50 | 820 (31.4) | 38,247 (39.3) | ref |
| 50–60 | 746 (28.6) | 29,797 (30.6) | 0.003 |
| >60 | 1046 (40.0) | 29,221 (30.0) | <0.001 |
| Urban area | 1189 (45.5) | 42,403 (43.6) | 0.055 |
| South area | 1468 (56.2) | 55,899 (57.5) | 0.079 |
| Primary school and lower | 1467 (56.2) | 51,576 (53.0) | 0.527 |
| Current smoker a | 856 (32.8) | 30,287 (31.1) | 0.567 |
| Daily alcohol drinker | 268 (10.3) | 9289 (9.6) | 0.997 |
| Daily tea drinker | 723 (27.7) | 26,262 (27.0) | 0.817 |
| PA (MET-h/d) | 18.2 ± 13.4 | 19.9 ± 13.8 | 0.046 |
| BMI (kg/m2) | 23.6 ± 3.5 | 23.7 ± 3.5 | 0.710 |
| BMI (kg/m2) groups | |||
| <18.5 | 152 (5.8) | 5027 (5.2) | 0.674 |
| 18.5–23.9 | 1316 (50.4) | 49,373 (50.8) | ref |
| 24.0–27.9 | 880 (33.7) | 31,991 (32.9) | 0.719 |
| ≥28.0 | 264 (10.1) | 10,874 (11.2) | 0.059 |
| Family history of cancer | 419 (16.0) | 16,168 (16.6) | 0.312 |
Categorical variables were presented as crude n (%), while continuous variables were presented as crude means ± SDs. All P-values were adjusted for age, sex and 10 study regions, as appropriate. aCurrent-smoker included former smokers who had stopped smoking because of illness.
mCAs mosaic chromosomal alterations, MET metabolic equivalent of task, PA physical activity, BMI body mass index