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AUC for predicting MCPyV status. Mutation signatures 1 and 7 were described by Alexandrov and colleagues (23).
| AUC | 2L+ cohort | 1L cohort | ||
|---|---|---|---|---|
| PCR | IHC | PCR | IHC | |
| Total mutations | 0.77 | 0.71 | 1 | 0.98 |
| TMB | 0.77 | 0.67 | 1 | 0.99 |
| Mutation signature 1 | 0.80 | 0.64 | 1 | 0.97 |
| Mutation signature 7 | 0.70 | 0.70 | 1 | 0.98 |
