Table I.
Overview of the included studies.
| No. of patients | ||||||||
|---|---|---|---|---|---|---|---|---|
|
|
||||||||
| Variable 1 | Variable 2 | No. of included studies | Serous POS | Serous total | Case POS | Case total | Control POS | Control total |
| Country | Africa | 2 | 6 | 53 | 18 | 170 | 0 | 0 |
| Asia | 21 | 45 | 563 | 426 | 1,691 | 32 | 677 | |
| Europe | 13 | 35 | 425 | 102 | 763 | 47 | 252 | |
| North America | 7 | 0 | 30 | 9 | 130 | 0 | 35 | |
| Method | PCR | 36 | 58 | 947 | 483 | 2,498 | 68 | 871 |
| IHC | 1 | 3 | 26 | 3 | 31 | 0 | 18 | |
| PCR/IHC | 1 | 9 | 53 | 9 | 53 | 0 | 0 | |
| ISH | 2 | 15 | 24 | 41 | 90 | 11 | 62 | |
| PCR/ISH | 2 | 1 | 6 | 17 | 31 | 0 | 8 | |
| PCR/Southern blot | 1 | 0 | 15 | 2 | 51 | 0 | 5 | |
| Sample type | FFPE | 29 | 46 | 768 | 466 | 2,218 | 77 | 805 |
| FFPE, frozen tissue | 1 | 7 | 14 | 10 | 17 | 0 | 0 | |
| Frozen tissue | 9 | 27 | 132 | 69 | 287 | 2 | 137 | |
| Fresh tissue | 4 | 6 | 157 | 10 | 232 | 0 | 22 | |
FFPE, formalin-fixed paraffin-embedded; IHC, Immunohistochemistry; ISH, in situ hybridization; POS, positive.