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| Estimate | Mortality HR (95% CI) | 12-mo Survival probability (95% CI) | |
|---|---|---|---|
| Pembrolizumab combination | Chemotherapy only | ||
| KEYNOTE-189 (ITT) | 0.49 (0.38-0.64) | 0.69 (0.64-0.74) | 0.49 (0.42-0.56) |
| EHR (ITT) | 0.95 (0.78-1.16) | 0.60 (0.54-0.65) | 0.58 (0.55-0.62) |
| EHR (PP) | 1.15 (0.96-1.37) | 0.72 (0.42-1.00) | 0.58 (0.18-1.00) |
Abbreviations: EHR, electronic health record; HR, hazard ratio; ITT, intention to treat; PP, per protocol.
