Table 1.
Studies that report the amino acid (AA) concentration in mature human milk that were published before 2023 and not included in the present dataset.
| Study | Exclusion criteria |
|---|---|
| Atkinson et al. (52) | Data from collection periods earlier than 1 month post-partum |
| Beach et al. (53) | Non-standard amino acid analysis (microbiological) |
| Block and Bolling (54) | Non-standard amino acid analysis (microbiological) |
| Chathyushya et al. (55) | Only breast milk of 1 week post-partum collected |
| Close and Van De Walle (56) | Inadequate information on breast milk sample |
| Darling et al. (57) and Darling (58) | Data from collection periods earlier than 1 month post-partum |
| Davis et al. (59) | Data reported in another publication that was included (duplicate data) |
| DeSantiago et al. (60) | Health criteria of lactating mothers not met |
| Faus et al. (61) | Total AAs not determined |
| Feng et al. (62) | Data reported in another publication that was included (duplicate data) |
| Ferreira (63) | Data from collection periods earlier than 1 month post-partum |
| Filippova and Aronova (64) | Method for AA determination not reported |
| Giuffrida et al. (65) | Total AAs not determined |
| Guo et al. (66) | Single milk donor |
| Hanning et al. (67) | Data from collection periods earlier than 1 month post-partum |
| Heine et al. (51) | Data reported in another publication that was included (duplicate data) |
| Jarvenpaa et al. (68) | Data reported in another publication that was included (duplicate data) |
| Lemons et al. (69) | Total AAs not determined |
| Macy (70) and Macy and Kelly (71) | Non-standard amino acid analysis (microbiological) |
| Miller et al. (72) | Non-standard amino acid analysis (microbiological) |
| Mitton and Garlick (73) | Inadequate information on breast milk sample |
| Moya-Alvarez et al. (74) | Health criteria of lactating mothers not met (many with malnutrition) |
| Motil et al. (75) | Total AAs not determined |
| Nagasawa et al. (76) | AA profile of breast milk casein only |
| Nayman et al. (77) | Non-standard amino acid analysis (microbiological) |
| Nwachoko et al. (78) | Results reported in mg AA/100 g protein but no total N or protein data provided |
| Pang et al., 2019 (79) | Inadequate information on methodology; text in Mandarin |
| Picone et al. (80) | Inadequate information on methodology |
| Purkiewicz et al. (81) | Data from collection periods earlier than 1 month post-partum |
| Räihä et al. (82) | Data reported in another publication that was included (duplicate data) |
| Rassin et al. (83) | Lactation stage unclear |
| Renner (84) | Data reported in another publication that was included (duplicate data) |
| Rigo et al. (85) | Data reported in another publication that was included (duplicate data) |
| Saben et al. (86) | Total AAs not determined |
| Saito et al. (87) | Non-standard amino acid analysis (microbiological) |
| Sarwar et al. (88) | Data from collection periods earlier than 1 month post-partum |
| Scott et al. (89) | Inadequate information on methodology |
| Shaikhiev (90) | Text in Russian (Cyrillic) |
| Soupart et al. (91) | Lactation stage unclear |
| Tarján et al. (92) | Total AAs not determined |
| Tikanoja et al. (93) | Lactation stage unclear |
| Van Sadelhoff et al. (94) | Total AAs not determined |
| Volz et al. (95) | Data reported in another publication that was included (duplicate data) |
| Wei et al. (96) | Total AAs not determined; non-standard amino acid analysis; not representative of mature milk |
| Williamson (97) | Non-standard amino acid analysis (colorimetric) |
| Woodward (98) | AA profile of breast milk casein only |