Table 4.
Cross sorting between vaccination status, clinical appearance and toxigenicity of strains and nasopharyngeal carriage of diphtheria.
| Clinic | Immunisation status: immunized against diphtheria | p | |||||
|---|---|---|---|---|---|---|---|
| No = 15 | Yes = 12 | ||||||
| n | (%) | [CI95%] | n | (p) | [CI95%] | ||
| Ulcerated lesion | 13 | (61.9) | [38.8-85.1] | 8 | (38.1) | [14.9-61.2] | 0.62 |
| Pseudomembrane | 0 | (NaN) | [NaN-NaN] | 0 | (NaN) | [NaN-NaN] | 1 |
| Nodular lesion | 2 | (66.7) | [0-100] | 1 | (33.3) | [0-100] | 1 |
| Papular lesion | 4 | (100) | [87.5-100] | 0 | (0) | [0-12.5] | 0.113 |
| Necrotic lesion | 1 | (20) | [0-65.1] | 4 | (80) | [34.9-100] | 0.128 |
| Vesicular lesion | 1 | (33.3) | [0-100] | 2 | (66.7) | [0-100] | 0.556 |
| Pustular lesion | 3 | (75) | [20.1-100] | 1 | (25) | [0-79.9] | 0.614 |
| Crusty lesion | 5 | (55.6) | [17.5-93.6] | 4 | (44.4) | [6.4-82.5] | 1 |
| Painful lesion | 6 | (50) | [17.5-82.5] | 6 | (50) | [17.5-82.5] | 0.692 |
| Pruritic lesion | 3 | (75) | [20.1-100] | 1 | (25) | [0-79.9] | 0.614 |
| Edema | 7 | (70) | [36.6-100] | 3 | (30) | [0-63.4] | 0.678 |
| Peripheral desquamation | 3 | (42.9) | [0-86.7] | 4 | (57.1) | [13.3-100] | 0.378 |
| Number of lesions | 0.883 | ||||||
| 1 | 7 | (63.6) | [30.7-96.6] | 4 | (36.4) | [3.4-69.3] | |
| 2–5 | 4 | (57.1) | [13.3-100] | 3 | (42.9) | [0-86.7] | |
| >5 | 4 | (44.4) | [6.4-82.5] | 5 | (55.6) | [17.5-93.6] | |
| Size of lesions | 0.188 | ||||||
| <1 cm | 5 | (71.4) | [30.8-100] | 2 | (28.6) | [0-69.2] | |
| 1–5 cm | 8 | (57.1) | [27.6-86.6] | 6 | (42.9) | [13.4-72.4] | |
| >5 cm | 0 | (0) | [0-16.7] | 3 | (100) | [83.3-100] | |
| Toxinogen Corynebacterium | 0.233 | ||||||
| No | 5 | (41.7) | [9.6-73.7] | 7 | (58.3) | [26.3-90.4] | |
| Yes | 10 | (71.4) | [44.2-98.7] | 4 | (28.6) | [1.3-55.8] | |
| Nasopharyngeal carriage | 0.513 | ||||||
| Positive | 4 | (80) | [34.9-100] | 1 | (20) | [0-65.1] | |
| Negative | 8 | (53.3) | [24.8-81.9] | 7 | (46.7) | [18.1-75.2] | |