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. 2024 Sep 26;13(1):2408324. doi: 10.1080/22221751.2024.2408324

Table 5.

Clinical appearance of cutaneous diphtheria and complications according to toxigenic status.

Clinic Toxinogen p
No N = 34 Yes N = 22
n (%) [CI95%] n (p) [CI95%]
Ulcerated lesion 28 (62.2) [46.9-77.5] 17 (37.8) [22.5-53.1] 0.498
Erythemato purpulish ulceration border 18 (69.2) [49.6-88.9] 8 (30.8) [11.1-50.4] 0.343
Raised border 6 (50.0) [17.5-82.5] 6 (50.0) [17.5-82.5] 0.483
Indurated border 5 (45.5) [11.5-79.4] 6 (54.5) [20.6-88.5]  0.281
Pseudomembrane 2 (100.0) [75.0-100.0] 0 (0.0) [0.0-25.0] 0.509
Nodular lesion 2 (40.0) [0.0-92.9] 3 (60.0) [7.1-100.0] 1.000
Papular lesion 4 (50.0) [9.1-90.9] 4 (50.0) [9.1-90.9] 0.700
Necrotic lesion 6 (75.0) [38.7-100.0] 2 (25.0) [0.0-61.3] 0.449
Vesicular lesion 3 (60.0) [7.1-100.0] 2 (40.0) [0.0-92.9] 1.000
Pustular lesion 4 (44.4) [6.4-82.5] 5 (55.6) [17.5-93.6] 0.457
Crusty lesion 10 (55.6) [29.8-81.3] 8 (44.4) [18.7-70.2] 0.769
Painful lesion 19 (67.9) [48.8-86.9] 9 (32.1) [13.1-51.2] 0.171
Pruritic lesion 2 (25.0) [0.0-61.3] 6 (75.0) [38.7-100.0] 0.052
Edema 10 (58.8) [32.5-85.2] 7 (41.2) [14.8-67.5] 1.000
Peripheral desquamation 6 (54.5) [20.6-88.5] 5 (45.5) [11.5-79.4] 0.744
Number of lesions             0.532
 1 16 (69.6) [48.6-90.5] 7 (30.4) [9.5-51.4]  
 2–5 11 (52.4) [28.6-76.1] 10 (47.6) [23.9-71.4]  
 >5 7 (58.3) [26.3-90.4] 5 (41.7) [9.6-73.7]  
Size of lesions             0.374
 <1 cm 7 (53.8) [22.9-84.8] 6 (46.2) [15.2-77.1]  
 1–5 cm 15 (60.0) [38.8-81.2] 10 (40.0) [18.8-61.2]  
 >5 cm 11 (78.6) [53.5-100.0] 3 (21.4) [0.0-46.5]  
Complications              
Arthritis 4 (100.0) [87.5-100.0] 0 (0.0) [0.0-12.5] 0.539
Bacteraemia 3 (100.0) [83.3-100.0] 0 (0.0) [0.0-16.7] 0.246
Peripheral neuropathy 0 (0.0) [0.0-16.7] 3 (100.0) [83.3-100.0] 0.010
Respiratory distress 1 (100.0) [50.0-100.0] 0 (0.0) [0.0-50.0] 1.000