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. 2024 Sep 30;10:35. doi: 10.1186/s40813-024-00383-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Experimental design of the studies including timing of vaccination (safety gun), blood sampling (blood tube), oestrus detection, and slaughter (pig icon) and: (A) pre-clinical study (n = 57) with early (A1) and late priming (A2), (B) the 1st clinical study with late priming (n = 80), and (C) 2nd clinical study with early priming (n = 40)