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Simulated TXA concentration versus time graph. Simulated curves representing loading dose 30 mg/kg with infusion of 10 mg/kg/h (solid line) and loading dose 30 mg/kg only without infusion (dashed line). Modified from ‘Tranexamic acid and perioperative bleeding in children: what do we still need to know?’ by Goobie S. M. and Faraoni D. (2019), Curr Opin Anesthesiol, 32(3), Fig. 1 (Goobie and Faraoni 2019)
