Table 1.

Demographic and baseline characteristics

Variable	All patients N = 129	Single bolus (Group A) N = 60	Bolus + infusion (Group B) N = 69	p-value
Age, years	14.84 ± 3.36	14.98 ± 3.90	14.71 ± 2.84	0.647
Sex
Male	14 (10.9)	7 (11.7)	7 (10.1)	0.782
Female	115 (89.1)	53 (88.3)	62 (89.9)
Weight, kg	44.26 ± 7.72	44.83 ± 8.58	43.77 ± 6.91	0.441
Height, cm	155.65 ± 7.27	154.97 ± 8.08	156.24 ± 6.49	0.331
Body blood volume, mLa	3045.40 ± 448.64	3051.97 ± 501.69	3039.69 ± 400.53	0.879
Haemoglobin, g/dL	13.50 ± 1.05	13.27 ± 1.09	13.70 ± 0.98	0.021
Haematocrit, %	0.41 ± 0.03	0.40 ± 0.03	0.41 ± 0.03	0.015
INR	1.08 ± 0.08	1.09 ± 0.07	1.08 ± 0.08	0.602
aPTT, s	35.78 ± 3.56	35.41 ± 3.14	36.11 ± 3.88	0.262
Fibrinogen, g/L	2.69 ± 0.47	2.66 ± 0.44	2.71 ± 0.50	0.557

Data shown are mean ± standard deviation or frequency (percentage)

Abbreviations: aPTT activated partial thromboplastin time, INR International normalised ratio

^aBody blood volume was calculated using Nadler equation