Fig. 6.

STRING network demonstrating protein associations in dysregulated GO-BP gene sets across the SETBP1 variant NPCs. GATA2 was identified as a key transcription factor linking to SETBP1 and many of the core enrichment genes in dysregulated gene sets in SETBP1 variant NPCs. Proteins directly associated with GATA2 are shown in orange, while proteins indirectly associated with GATA2 are shown in yellow. Level of confidence in association between proteins is represented by the thickness of the line