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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Nature. 2023 Jun 28;620(7972):181–191. doi: 10.1038/s41586-023-06252-9

Fig. 1 |. Major cell types of the adult human breast.

Fig. 1 |

a, Anatomy of the adult human breast and a pathological haematoxylin and eosin (H&E) section, with illustrations of the major breast cell types. b, The workflow of the HBCA project. c, Uniform manifold approximation and projection (UMAP) projection of scRNA-seq data from 714,331 cells integrated across 167 tissues from 126 women, showing 10 clusters that correspond to the major cell types. d, Consensus heat map of the top 7 genes expressed in each cell type cluster from averaged scRNA-seq data. e, UMAP representation of snRNA-seq data from 117,346 nuclei integrated across 24 tissues from 20 women, showing 11 cell type clusters. f, Consensus heat map of the top 7 genes expressed in each cell cluster from averaged snRNA-seq data. Adipo., adipocytes; perivasc., perivascular cells.