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. 2024 Oct 1;24:1166. doi: 10.1186/s12903-024-04882-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The impact of decellularized extracellular matrix derived from dental pulp stem cells on gingival fibroblast migration. The in vitro scratch experiment depicted GFs cultured on glass (control), collagen type I-coated (positive control), and dECM-coated substrates for 0, 6, 24, and 48 h. Scale bars represent 1000 μm. (B) Quantitative analysis revealed a significant decrease in the scratch closure of gingival fibroblasts cultured on dECM compared to control conditions at 0, 6, 24, and 48 h. (C) The graph depicts the proliferation rate of GFs cultured on dECM at days 1, 3, and 7. Statistical significance is denoted by asterisks, and bars indicate a significant difference between groups (p < 0.05)