Table 1.
Summary of baseline characteristics of the study population according to CumAIP quartile group
| CumAIP quartile | P-value | ||||
|---|---|---|---|---|---|
| Q1(-0.14-0.06) | Q2(0.06–0.12) | Q3(0.12–0.18) | Q4(0.18–0.45) | ||
| No. of subjects | 735 | 734 | 735 | 735 | |
| Age, years | 60.72 (9.06) | 60.20 (8.70) | 58.98 (8.67) | 57.61 (8.42) | < 0.001 |
| SBP, mmHg | 128.67 (21.22) | 129.69 (20.29) | 131.21 (21.55) | 133.14 (20.06) | < 0.001 |
| DBP, mmHg | 73.65 (11.67) | 75.48 (11.54) | 77.15 (12.01) | 78.95 (11.97) | < 0.001 |
| Height, m | 1.58 (0.08) | 1.57 (0.09) | 1.58 (0.08) | 1.58 (0.09) | 0.045 |
| Weight, kg | 55.30 (10.37) | 58.33 (11.14) | 61.98 (11.21) | 65.28 (11.58) | < 0.001 |
| TC, mg/dL | 193.84 (34.61) | 195.23 (39.91) | 197.63 (37.63) | 203.75 (39.66) | < 0.001 |
| LDL-C, mg/dL | 115.21 (95.10-132.41) | 120.43 (100.90-144.97) | 122.17 (101.68–147.10) | 114.43 (91.43-139.95) | < 0.001 |
| TG, mg/dL | 66.38 (54.87–82.31) | 92.92 (77.88-115.71) | 126.56 (103.55-157.09) | 206.21 (163.72-279.66) | < 0.001 |
| HDL-C, mg/dL | 64.95 (56.44-75.00) | 52.96 (45.62–60.70) | 46.39 (40.98–52.19) | 36.73 (32.09–42.53) | < 0.001 |
| hs-CRP, mg/L | 0.75 (0.45–1.71) | 0.85 (0.51–1.78) | 1.16 (0.63–2.18) | 1.31 (0.71–2.79) | 0.091 |
| Glucose, mmol/L | 107.50 (7.02) | 107.71 (8.04) | 108.40 (7.93) | 110.03 (8.16) | < 0.001 |
| HbA1c, % | 5.22 (0.41) | 5.23 (0.42) | 5.24 (0.42) | 5.22 (0.44) | 0.800 |
| UA, mg/dL | 4.13 (3.45–4.99) | 4.16 (3.55–5.03) | 4.40 (3.71–5.21) | 4.62 (3.87–5.49) | < 0.001 |
| Cr, mg/dL | 0.75 (0.65–0.86) | 0.75 (0.64–0.87) | 0.76 (0.66–0.88) | 0.76 (0.66–0.88) | 0.405 |
| BUN, mg/dL | 15.80 (13.11–19.12) | 15.08 (12.69–18.42) | 14.96 (12.63–18.23) | 14.82 (12.46–17.59) | < 0.001 |
| Gender | < 0.001 | ||||
| Male | 400 (54.42%) | 344 (46.87%) | 309 (42.04%) | 304 (41.36%) | |
| Female | 335 (45.58%) | 390 (53.13%) | 426 (57.96%) | 431 (58.64%) | |
| Education, n (%) | 0.031 | ||||
| Below primary | 364 (49.52%) | 371 (50.54%) | 361 (49.12%) | 321 (43.67%) | |
| Primary schools | 176 (23.95%) | 157 (21.39%) | 160 (21.77%) | 165 (22.45%) | |
| Middle school | 150 (20.41%) | 148 (20.16%) | 143 (19.46%) | 173 (23.54%) | |
| High school and above | 45 (6.12%) | 58 (7.90%) | 71 (9.66%) | 76 (10.34%) | |
| Marital status | 0.012 | ||||
| Married | 638 (86.80%) | 628 (85.56%) | 637 (86.67%) | 668 (90.88%) | |
| Other | 97 (13.20%) | 106 (14.44%) | 98 (13.33%) | 67 (9.12%) | |
| Registered residence | < 0.001 | ||||
| Village | 641 (87.21%) | 619 (84.33%) | 606 (82.45%) | 578 (78.64%) | |
| City | 94 (12.79%) | 115 (15.67%) | 129 (17.55%) | 157 (21.36%) | |
| CVD | 0.004 | ||||
| Yes | 72 (9.80%) | 95 (12.94%) | 116 (15.78%) | 109 (14.83%) | |
| No | 663 (90.20%) | 639 (87.06%) | 619 (84.22%) | 626 (85.17%) | |
| Stroke | 0.033 | ||||
| Yes | 9 (1.22%) | 19 (2.59%) | 16 (2.18%) | 26 (3.54%) | |
| No | 726 (98.78%) | 715 (97.41%) | 719 (97.82%) | 709 (96.46%) | |
| Hypertension | < 0.001 | ||||
| No | 480 (65.31%) | 448 (61.04%) | 430 (58.50%) | 359 (48.84%) | |
| Yes | 255 (34.69%) | 286 (38.96%) | 305 (41.50%) | 376 (51.16%) | |
| Smoking status | 0.007 | ||||
| Never | 426 (57.96%) | 466 (63.49%) | 492 (66.94%) | 473 (64.35%) | |
| Current | 244 (33.20%) | 213 (29.02%) | 178 (24.22%) | 196 (26.67%) | |
| Quit | 65 (8.84%) | 55 (7.49%) | 65 (8.84%) | 66 (8.98%) | |
| Drinking status | < 0.001 | ||||
| Current | 235 (31.97%) | 182 (24.80%) | 160 (21.77%) | 168 (22.86%) | |
| Never | 454 (61.77%) | 512 (69.75%) | 533 (72.52%) | 509 (69.25%) | |
| Quit | 46 (6.26%) | 40 (5.45%) | 42 (5.71%) | 58 (7.89%) | |
Values were expressed as mean (standard deviation) or medians (quartile interval) or n (%)
SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, haemoglobin A1c; HDL-C, high‐density lipoprotein‐cholesterol; hs‐CRP, high‐sensitivity C‐reactive protein; LDL‐C, low‐density lipoprotein‐cholesterol; TC, total cholesterol; TG, triglycerides; UA, uric acid; BUN, blood urea nitrogen; Cr, creatinine; CumAIP, cumulative atherogenic index of plasma