FIG. 3.

SV-induced death of cortical neurons is ameliorated by NMDA receptor antagonists. Cortical cells were infected at an MOI of 5 with SV with or without 300 μM APV or 3 μM MK-801. Viability was assayed by PI exclusion. The results from four independent experiments, each done in triplicate, are shown and are presented as the mean percent viability ± SD (∗, P = 0.0005 for APV + SV versus SV; #, P = 0.004 for MK-801 + SV versus SV; +, P = 0.018 for APV + SV versus SV by Student's t test).