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Compound 2 and 1 MIC values against representative γ-lactam susceptible/carbapenem-resistant K. pneumoniae and P. aeruginosa strains (23 each). Except for one isolate, YUKP-39, compound 2 maintains microbiologic potency against MDR Gram-negative rods previously described for this γ-lactam-siderophore class (see also Supplemental Table 1, page 18).
