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. 2024 Oct 1;132(10):107701. doi: 10.1289/EHP14729

Table 1.

Baseline characteristics of Sister Study participants by case status, enrolled 2003–2009.

Characteristics Ovarian cancer cases (n=249) All (n=40,308)a
Age (y) [n (%)]
<40 5 (2.0) 1,966 (4.9)
 40–49 52 (20.9) 10,666 (26.5)
 50–59 90 (36.1) 15,701 (38.9)
 60–69 79 (31.7) 9,853 (24.4)
 70–79 23 (9.2) 2,122 (5.3)
Race/ethnicity [n (%)]
 Black, including Hispanic 20 (8.0) 3,349 (8.3)
 Hispanic/Latina 5 (2.0) 1,254 (3.1)
 Non-Hispanic White 220 (88.4) 34,401 (85.4)
 Other racesb 4 (1.6) 1,304 (3.2)
Educational attainment [n (%)]
 High school or less 46 (18.5) 5,734 (14.2)
 Some college 87 (34.9) 13,176 (32.7)
 College graduate or more 116 (46.6) 21,398 (53.1)
nSES score [median (IQR)]c 0.22 (0.96, 0.38) 0.29 (1.07, 0.36)
Menopause status [n (%)]
 Premenopausal 80 (32.1) 16,458 (40.8)
 Postmenopausal 169 (67.9) 23,845 (59.2)
US Census region [n (%)]
 Northeast 39 (15.7) 7,389 (18.3)
 Midwest 73 (29.3) 11,040 (27.4)
 South 78 (31.3) 13,105 (32.5)
 West 59 (23.7) 8,774 (21.8)
Urbanicity [n (%)]
 Urban 39 (15.7) 7,695 (19.1)
 Suburban 98 (39.3) 16,166 (40.1)
 Rural/small town/other 112 (45.0) 16,447 (40.8)
12-month NO2 concentrations (ppb) [median (IQR)] 8.9 (5.8–12.2) 8.4 (5.8–11.8)
12-month PM2.5 concentrations (μg/m3) [median (IQR)] 11.0 (8.8–12.8) 10.7 (8.7–12.4)
12-month O3 concentrations (ppb) [median (IQR)] 26.3 (24.4–29.0) 26.6 (24.4–28.8)

Note: IQR, interquartile ranges; NO2, nitrogen dioxide; nSES, neighborhood socioeconomic status; O3, ozone; PM2.5, particulate matter 2.5μm in diameter.

a

Excluded women who withdrew from the study (n=5), had a prevalent or uncertain ovarian cancer history (n=235), pre-baseline bilateral oophorectomy or unknown number of ovaries removed (n=9,010), missing air pollutant exposure data (n=825), missing race/ethnicity (n=13), missing educational attainment (n=3), missing nSES score (n=253), missing US Census region (n=19), or zero follow-up time (n=213).

b

Other races includes American Indian/Alaskan Native, Asian, and Native Hawaiian or other Pacific Islander.

c

An index developed using 16 tract-level measures of educational attainment, occupation, income, wealth, poverty, employment status, and housing characteristics from the US Census and American Community Survey, with higher index indicating lower nSES and vice versa.