TABLE 1.
Demographics and Characteristics of Subjects With TBI on VV ECMO
| All Subjects (n = 36) | Survivors (n = 26) | Nonsurvivors (n = 10) | p | |
|---|---|---|---|---|
| Age, median (IQR), y | 29 (23.5–39) | 28.5 (21–40) | 30.5 (24–37) | 0.86 |
| Race/ethnicity, n (%) | 0.53 | |||
| White | 16 (44) | 13 (50) | 3 (30) | |
| Hispanic | 2 (6) | 1 (4) | 1 (10) | |
| African American | 16 (44) | 10 (38) | 6 (60) | |
| Other | 2 (6) | 2 (8) | (0) | |
| Sex, n (%) | ||||
| Male | 29 (81) | 21 (51) | 8 (80) | 0.96 |
| BMI, median (IQR) | 27.2 (23.45–32.35) | 27.2 (22.4–30.1) | 28.3 (23.9–35.4) | 0.45 |
| Past medical history, n (%) | — | |||
| Asthma/COPD | 1 (3) | 1 (4) | 0 (0) | |
| DM | 1 (3) | 1 (4) | 0 (0) | |
| CAD | 2 (6) | 1 (4) | 1 (10) | |
| Liver disease | 1 (3) | 1 (4) | 0 (0) | |
| Substance abuse | 4 (11) | 3 (12) | 1 (10) | |
| VV ECMO cannulation strategy, n (%) | 0.83 | |||
| IJ/fem | 25 (69) | 18 (69) | 7 (70) | |
| Fem/fem | 10 (28) | 7 (27) | 3 (30) | |
| Dual lumen | 1 (3) | 1 (4) | 0 (0) | |
| Time from arrival to cannulation, median (IQR), h | 16 (3.5–72) | 13 (3–72) | 19 (4–72) | 0.41 |
| Decannulated, n (%) | 27 (75) | 26 (100) | 1 (10) | — |
| Use of CRRT during ECMO run, n (%) | 18 (50) | 11 (42) | 7 (70) | 0.14 |
| Cardiac arrest before cannulation, n (%) | 14 (39) | 8 (31) | 6 (60) | 0.11 |
| Time from admission to cannulation, median (IQR), h | 16 (3.5–72) | 13 (3–72) | 19 (4–72) | 0.76 |
| Hours on ECMO, median (IQR) | 212.5 (120–348) | 240 (167–336) | 72 (46–360) | 0.04 |
| Hospital LOS, median (IQR) | 33.5 (11.5–51.5) | 45 (32–57) | 6.5 (3–15) | <0.001 |
| Ventilator days, median (IQR) | 19 (9–34.5) | 23.5 (18–36) | 4 (3–14) | <0.001 |
| Discharge location, n (%) | — | — | — | |
| Home | 2 (6) | |||
| Rehab | 24 (94) | |||
| Ventilator requirements at discharge, n (%) | — | — | — | |
| Room air | 17 (65) | |||
| Trach collar | 9 (35) | |||
| Survival to discharge, n (%) | 26 (72) | — | — | — |
BMI, body mass index; COPD, chronic obstructive lung disease; CRRT, continuous renal replacement therapy; CAD, coronary artery disease; DM, diabetes mellitus; ECMO, extracorporeal membrane oxygenation; fem, femoral; IJ, internal jugular; IQR, interquartile range; LOS, length of stay; rehab, rehabilitation.