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Animal groups and dosage of PastoCoAd vaccines
| Group | Mouse | Rabbit | Hamster | |||||
|---|---|---|---|---|---|---|---|---|
| Name | DC |
DC2
prime |
DC2 boost |
DC2
prime |
DC2 boost | DC2 boost | DC2 prime | DC2 boost |
| G1 | PBS (Mock) | PBS | -- | PBS | -- | -- | PBS | -- |
| G2 | rAd5 empty | 108 VP | -- | 109 VP | -- | -- | 1010 VP | -- |
| G3 | rAd5-S / SOBERANA |
108 VP | 10 µg | 109 VP | 30 µg | 30 µg | 1010 VP | 20 µg |
| G4 | rAd5-S & rAd5RBD-N mix | 5× 107 VP & 5× 107 VP | -- | 5× 108 VP & 5× 108 VP | -- | -- | 5× 109 VP & 5× 109 VP | -- |
DC: dose content; VP: viral particles; G: group
