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. 2024 Jun 10;86(10):5767–5775. doi: 10.1097/MS9.0000000000002256

Figure 2.

Figure 2

Silencing of ELK1 inhibits the proliferation and promotes apoptosis of MCF-7 cells. (A) Confirmation of ELK1 silencing by small interfering RNA (siRNA) using western blotting after 48 h of transfection. (B, C) Silencing of ELK1 inhibits the proliferation rate of MCF-7 cells by cell counting kit-8 and plate cloning experiments. (D) Silencing of ELK1 promotes apoptosis of MCF-7 cells by flow cytometry experiment. (E) Silencing of ELK1 upregulates the level of phosphatase and tensin homology (PTEN) expression. Mean±SD, n≥3, **P<0.01. ELK1, ETS-like gene 1.