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. 2024 Sep 18;12:1444801. doi: 10.3389/fchem.2024.1444801

TABLE 1.

Some examples of NDs used in drugs development and drugs delivery applications.


Nanodiscs type
Inserted Applications References
MSP nanodiscs Hydrophobic drugs&Cabazitaxel Cancer chemotherapy Pandey et al. (2021)
MSP nanodiscs (Lipids modified) Antibody-conjugated NDs for targeted cancer imaging Wong et al. (2020)
MSP nanodiscs Influenza virus M2 protein Antibody Discovery Yu et al. (2023)
apoA I-stabilized Nanodiscs (like MSP nanodiscs) Amphotericin B Anti-fungal drug delivery Cho et al. (2017)
ApoJ-stabilized Nanodiscs (like MSP nanodiscs) Alzheimer’s disease treatment Fernandez-de-Retana et al. (2017)
Peptide nanodiscs Adpgk & CM9 peptides Cancer vaccine Najafabadi et al. (2021)
Peptide nanodiscs DTX/CpG ICD inducer Kadiyala et al. (2019)
Peptide nanodiscs (KT peptide modified) T0901317 LXR agonist for diabetic nephropathy He et al. (2022)
Peptide nanodiscs ML355 Antiplatelet drug He et al. (2020)
SMA nanodiscs Bacterial Outer Membrane Antibacterial Vaccination Noh et al. (2022)

CBZ, cabazitaxel; DTX, docetaxel; KT, kidney targeting; ICD, immunogenic cell death.