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. 2024 Oct 1;14:22780. doi: 10.1038/s41598-024-73925-4

Table 4.

Correlations of disease polygenic risk score and codeine prescription count.

Data sources of genetic summary statistics Patient-level disease polygenic risk score Kendall’s Correlation (Tau) P-value

Psychiatric Genomics Consortium (PGC)

Pan-UK Biobank

(Broad Institute of MIT and Harvard)

Opioid use disorder 0.67 1.27E−2
Alcohol dependence 0.39 1.80E−1
Alzheimer’s dementia 0.22 4.77E−1
Attention deficit hyperactivity disorder 0.50 7.52E−2
Hyperhidrosis 0.17 6.12E−1
Standing height −0.22 4.77E−1
ECG heart rate 0.44 1.19E−1
Glaucoma −0.11 7.61E−1
Diabetic hypoglycemia 0.06 9.19E−1