Table 2.
Univariate and multifactorial analysis of OS in newly diagnosed MM patients.
| Clinical character | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR(95%CI) | P value | HR(95%CI) | P value | |
| Age(>60) | 1.898(1.455–2.477) | 0.000 | 1.300(0.982–1.722) | 0.067 |
| Hemoglobin(< 100 g/L) | 1.680(1.264–2.233) | 0.000 | 1.053(0.763–1.454) | 0.754 |
| Lactate dehydrogenase (> 245U/L) | 1.605(1.160–2.219) | 0.004 | 1.447(1.033–2.027) | 0.032 |
| β2 -microglobulin (> 3.5 mg/L) | 2.456(1.784–3.380) | 0.000 | 1.728(1.203–2.484) | 0.003 |
| Creatinine(> 177 µmol/L) | 2.231(1.704–2.922) | 0.000 | 1.563(1.152–2.122) | 0.004 |
|
Blood calcium (> 2.75 mmol/L) |
2.623(1.830–3.760) | 0.000 | 1.576(1.046–2.374) | 0.030 |
| POD24 | 2.100(1.631–2.704) | 0.000 | 1.956(1.507–2.541) | 0.000 |
| Treatment (without bortezomib) | 0.617(0.480–0.794) | 0.000 | 0.638(0.490–0.831) | 0.001 |
| Chromosomal abnormality | 1.248(0.940–1.657) | 0.126 | ||
| Non-transplantion | 0.111(0.052–0.235) | 0.000 | 0.171(0.079–0.371) | 0.000 |