Table 2.
Aneurysmal dilatation (n = 16) | No aneurysmal dilatation (n = 57) | P | Occlusion (n = 5) | No occlusion (n = 68) | P | |
---|---|---|---|---|---|---|
Male | 8 (50) | 33 (57.9) | 0.574 | 3 (60) | 38 (55.9) | 1.000 |
Age in years, mean ± SD | 49.5 ± 8.07 | 46.0 ± 10.5 | 0.224 | 49 ± 5.1 | 46.8 ± 10.1 | 0.613 |
Hypertension | 6 (37.5) | 24 (42.1) | 0.741 | 3 (60) | 27 (39.7) | 0.396 |
Diabetes | 1 (6.25) | 1 (1.8) | 0.393 | 0 (0) | 2 (2.9) | 1.000 |
Hyperlipidemia | 2 (12.5) | 11 (19.3) | 0.720 | 0 (0) | 13 (19.1) | 0.578 |
Smoking | 3 (18.9) | 20 (35.1) | 0.214 | 2 (40) | 21 (30.9) | 0.647 |
Old CVA | 0 (0) | 3 (5.3) | 1.000 | 0 (0) | 3 (4.4) | 1.000 |
Family history | 2 (12.5) | 13 (22.8) | 0.497 | 0 (0) | 15 (22.1) | 0.576 |
Initial symptom | < 0.001* | 1.000 | ||||
Ischemic symptom | 4 (25) | 45 (78.9) | 3 (60) | 46 (67.7) | ||
Headache | 12 (75) | 12 (21.1) | 2 (40) | 22 (32.4) | ||
Recurred or newly developed symptom | 1 (6.3) | 15 (26.3) | 0.168 | 1 (20) | 15 (22.1) | 1.000 |
VW-MRI | ||||||
Dissecting flap | 13 (81.3) | 50 (87.7) | 0.681 | 4 (80) | 59 (86.8) | 0.532 |
Double lumen | 9 (56.3) | 20 (35.1) | 0.126 | 0 (0) | 29 (42.7) | 0.150 |
Intramural hematoma | 10 (62.5) | 52 (91.2) | 0.011* | 5 (100) | 57 (83.8) | 1.000 |
Increased outer diameter | 15 (93.8) | 7 (12.3) | < 0.001* | 0 (0) | 22 (32.4) | 0.314 |
Onion-skin appearance | 5 (31.3) | 17 (29.8) | 1.000 | 3 (60) | 19 (27.9) | 0.157 |
Wall enhancement | 13 (81.3) | 31 (54.4) | 0.052 | 2 (40) | 42 (61.8) | 0.380 |
Preserved patency | 15 (93.8) | 38 (66.7) | 0.054 | 1 (20) | 52 (76.5) | 0.018* |
Eccentricity indexa | 0.49 (-0.07–0.86) | 0.75 (0.49–0.86) | 0.118 | 0.6 (0.5–0.72) | 0.74 (0.43–0.86) | 0.454 |
Remodeling indexa | 3.2 (2.44–4.22) | 2.06 (1.6–3) | 0.004* | 2.53 (2.4–4.64) | 2.33 (1.64–3.23) | 0.303 |
Normalized wall indexa | 0.66 (0.53–0.77) | 0.57 (0.5–0.69) | 0.212 | 0.66 (0.56–0.69) | 0.57 (0.51–0.7) | 0.786 |
rsIMHa | 1.63 (1.35–2.35) | 2 (1.48–3.53) | 0.086 | 3.13 (2.21–3.89) | 1.87 (1.43–3.21) | 0.247 |
TOF-MRA | ||||||
Dissecting flap | 12 (75) | 35 (61.4) | 0.316 | 3 (60) | 44 (64.7) | 1.000 |
Double lumen | 5 (31.3) | 9 (15.8) | 0.278 | 0 (0) | 14 (20.6) | 0.576 |
Intramural hematoma | 7 (43.8) | 26 (45.6) | 0.895 | 4 (80) | 29 (42.7) | 0.169 |
Increased outer diameter | 13 (81.3) | 9 (15.8) | < 0.001* | 0 (0) | 22 (32.4) | 0.314 |
Preserved patency | 14 (87.5) | 35 (61.4) | 0.050 | 1 (20) | 48 (70.6) | 0.037 |
Remodeling indexa | 2.87 (2.02–4.35) | 1.97 (1.19–2.77) | 0.005* | 2.45 (2.06–2.65) | 2.1 (1.28–3.33) | 0.860 |
rsIMHa | 2.2 (1.27–2.64) | 1.56 (1.13–2.53) | 0.142 | 2.53 (1.86–2.85) | 1.62 (1.16–2.59) | 0.110 |
Data are expressed as the number of cases with percentages in parentheses unless otherwise indicated. aData are expressed as median (interquartile range). VW-MR vessel wall magnetic resonance image; TOF-MRA time of flight-magnetic resonance angiography; SD standard deviation; CVA cerebrovascular accident; rsIMH relative signal intensity of intramural hematoma. * indicates statistical significance (P < 0.05).