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. 2024 Oct 1;14:22777. doi: 10.1038/s41598-024-73418-4

Table 2.

Comparison of baseline features according to final morphology.

Aneurysmal dilatation (n = 16) No aneurysmal dilatation (n = 57) P Occlusion (n = 5) No occlusion (n = 68) P
Male 8 (50) 33 (57.9) 0.574 3 (60) 38 (55.9) 1.000
Age in years, mean ± SD 49.5 ± 8.07 46.0 ± 10.5 0.224 49 ± 5.1 46.8 ± 10.1 0.613
Hypertension 6 (37.5) 24 (42.1) 0.741 3 (60) 27 (39.7) 0.396
Diabetes 1 (6.25) 1 (1.8) 0.393 0 (0) 2 (2.9) 1.000
Hyperlipidemia 2 (12.5) 11 (19.3) 0.720 0 (0) 13 (19.1) 0.578
Smoking 3 (18.9) 20 (35.1) 0.214 2 (40) 21 (30.9) 0.647
Old CVA 0 (0) 3 (5.3) 1.000 0 (0) 3 (4.4) 1.000
Family history 2 (12.5) 13 (22.8) 0.497 0 (0) 15 (22.1) 0.576
Initial symptom < 0.001* 1.000
 Ischemic symptom 4 (25) 45 (78.9) 3 (60) 46 (67.7)
 Headache 12 (75) 12 (21.1) 2 (40) 22 (32.4)
Recurred or newly developed symptom 1 (6.3) 15 (26.3) 0.168 1 (20) 15 (22.1) 1.000
VW-MRI
 Dissecting flap 13 (81.3) 50 (87.7) 0.681 4 (80) 59 (86.8) 0.532
 Double lumen 9 (56.3) 20 (35.1) 0.126 0 (0) 29 (42.7) 0.150
 Intramural hematoma 10 (62.5) 52 (91.2) 0.011* 5 (100) 57 (83.8) 1.000
 Increased outer diameter 15 (93.8) 7 (12.3) < 0.001* 0 (0) 22 (32.4) 0.314
 Onion-skin appearance 5 (31.3) 17 (29.8) 1.000 3 (60) 19 (27.9) 0.157
 Wall enhancement 13 (81.3) 31 (54.4) 0.052 2 (40) 42 (61.8) 0.380
 Preserved patency 15 (93.8) 38 (66.7) 0.054 1 (20) 52 (76.5) 0.018*
 Eccentricity indexa 0.49 (-0.07–0.86) 0.75 (0.49–0.86) 0.118 0.6 (0.5–0.72) 0.74 (0.43–0.86) 0.454
 Remodeling indexa 3.2 (2.44–4.22) 2.06 (1.6–3) 0.004* 2.53 (2.4–4.64) 2.33 (1.64–3.23) 0.303
 Normalized wall indexa 0.66 (0.53–0.77) 0.57 (0.5–0.69) 0.212 0.66 (0.56–0.69) 0.57 (0.51–0.7) 0.786
 rsIMHa 1.63 (1.35–2.35) 2 (1.48–3.53) 0.086 3.13 (2.21–3.89) 1.87 (1.43–3.21) 0.247
TOF-MRA
 Dissecting flap 12 (75) 35 (61.4) 0.316 3 (60) 44 (64.7) 1.000
 Double lumen 5 (31.3) 9 (15.8) 0.278 0 (0) 14 (20.6) 0.576
 Intramural hematoma 7 (43.8) 26 (45.6) 0.895 4 (80) 29 (42.7) 0.169
 Increased outer diameter 13 (81.3) 9 (15.8) < 0.001* 0 (0) 22 (32.4) 0.314
 Preserved patency 14 (87.5) 35 (61.4) 0.050 1 (20) 48 (70.6) 0.037
 Remodeling indexa 2.87 (2.02–4.35) 1.97 (1.19–2.77) 0.005* 2.45 (2.06–2.65) 2.1 (1.28–3.33) 0.860
 rsIMHa 2.2 (1.27–2.64) 1.56 (1.13–2.53) 0.142 2.53 (1.86–2.85) 1.62 (1.16–2.59) 0.110

Data are expressed as the number of cases with percentages in parentheses unless otherwise indicated. aData are expressed as median (interquartile range). VW-MR vessel wall magnetic resonance image; TOF-MRA time of flight-magnetic resonance angiography; SD standard deviation; CVA cerebrovascular accident; rsIMH relative signal intensity of intramural hematoma. * indicates statistical significance (P < 0.05).