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. 2024 Oct 1;14:22777. doi: 10.1038/s41598-024-73418-4

Table 5.

Comparisons of follow-up features between progressive enlargement and non-progressive aneurysmal dilatation.

Progressive enlargement of aneurysmal dilatation (n = 4) Non-progressive aneurysmal dilatation (n = 4) P
Time to MRI from symptom onset, days 216 (196–231) 182.0 (157–193.5) 0.083
Male 3 (75) 2 (50) 1.000
Age, years 48.5 (46–53.5) 42.5 (39–50.5) 0.245
Initial symptom 0.429
 Ischemic symptom 2 (50) 0 (0)
 Headache 2 (50) 4 (100)
Hypertension 2 (50) 0 (0) 0.429
Diabetes 1 (25) 0 (0) 1.000
Hyperlipidemia 1 (25) 1 (25) 1.000
Smoking 1 (25) 2 (50) 1.000
Old CVA 0 (0) 0 (0)
Family history 0 (0) 1 (25) 1.000
VW-MRI
 Dissecting flap 4 (100) 2 (50) 0.429
 Double lumen 4 (100) 1 (25) 0.143
 Intramural hematoma 4 (100) 1 (25) 0.143
 Increased outer diameter 4 (100) 4 (100) NA
 Onion-skin appearance 4 (100) 0 (0) 0.029*
 Wall enhancement 4 (100) 2 (50) 0.429
 Preserved patency 4 (100) 3 (75) 1.000
 Eccentricity index 0.84 (0.74–0.94) 0.54 (0.39–0.72) 0.059
 Remodeling index 16.56 (7.80–24.71) 2.39 (2.11–2.97) 0.021*
 Normalized wall index 0.98 (0.96–0.99) 0.67 (0.65–0.76) 0.021*
 rsIMH 4.60 (3.21–4.92) 1.38 (1.24–1.46) 0.021*
TOF-MRA
 Dissecting flap 4 (100) 2 (50) 0.429
 Double lumen 4 (100) 1 (25) 0.143
 Intramural hematoma 4 (100) 0 (0) 0.029*
 Increased outer diameter 3 (75) 3 (75) 1.000
 Preserved patency 3 (75) 3 (75) 1.000
 Remodeling index 12.96 (7.47–19.2) 2.02 (1.66–2.89) 0.021*
 rsIMH 2.67 (1.91–3.28) 1.07 (0.96–2.16) 0.149

Data are expressed as the number of cases with percentages in parentheses or median (interquartile range). VW-MRI vessel wall magnetic resonance image; TOF-MRA time of flight-magnetic resonance angiography; CVA cerebrovascular accident; rsIMH relative signal intensity of intramural hematoma. * indicates statistical significance (P < 0.05).