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. 2024 Aug 14;43(19):4324–4355. doi: 10.1038/s44318-024-00194-2

Figure 2. Chromatin is a major site for Cyclin B1 disappearance in RPE-1 cells.

Figure 2

(A) Representative fluorescence confocal images over time of an RPE-1 Cyclin B1-mEmerald+/+ cell progressing through mitosis after treatment with CenpEi and Reversine. Time is expressed as mm:ss. The scale bar corresponds to 10 μm. (B) Quantification of normalised Cyclin B1 fluorescence levels over time in RPE-1 Cyclin B1-mEmerald+/+ cells after treatment with CenpEi inhibitor (left) or a combination of CenpEi and Reversine (Right): n = 11 cells per condition, N = 3 independent experiments. Mean ± standard deviation are plotted. Source data are available online for this figure.