Table 4. Summary of the results of differences of change scores of GAD-7^a at 52 weeks using MMRM^b CBT^c components, week, CBT component by week interaction, university, age, and baseline scores as fixed effects, while participants were introduced as a random effect. Effect size was estimated by division of the estimated mean changes by the observed SD of baseline scores.

Component		Participants, n	Estimated least squares mean change scores of GAD-7 within groups (95% CI)	Within-group effect size for baseline-week 52 change score of GAD-7 (95% CI)	Estimated differences of baseline-week 52 change scores between groups (95% CI)	Effect size for differences of baseline-week 52 change scores between groups (95% CI)	P values
SM d					0.27 (−0.46 to 1)	0.08 (−0.14 to 0.3)	.47
	Presence	808	−1.28 (−1.82 to −0.74)	−0.38 (−0.55 to −0.22)
	Absence	818	−1.55 (−2.08 to −1.02)	−0.47 (−0.62 to −0.31)
BA e					−0.32 (−1.04 to 0.41)	−0.09 (−0.31 to 0.12)	.39
	Presence	817	−1.57 (−2.11 to −1.04)	−0.47 (−0.63 to −0.31)
	Absence	809	−1.26 (−1.79 to −0.72)	−0.38 (−0.54 to −0.22)
CR f					0.30 (−0.43 to 1.02)	0.09 (−0.13 to 0.31)	.42
	Presence	811	−1.27 (−1.79 to −0.74)	−0.38 (−0.54 to −0.22)
	Absence	815	−1.56 (−2.11 to −1.02)	−0.47 (−0.63 to −0.31)
AT g					0.14 (−0.59 to 0.86)	0.04 (−0.18 to 0.26)	.71
	Presence	814	−1.35 (−1.89 to −0.81)	−0.41 (−0.57 to −0.24)
	Absence	812	−1.48 (−2.01 to −0.95)	−0.44 (−0.60 to −0.29)
PS h					−0.01 (−0.73 to 0.72)	0 (−0.22 to 0.22)	.99
	Presence	811	−1.42 (−1.95 to −0.88)	−0.43 (−0.59 to −0.26)
	Absence	815	−1.41 (−1.95 to −0.87)	−0.42 (−0.59 to −0.26)

^aGAD-7: 7-item General Anxiety Disorder.

^bMMRM: mixed models for repeated measures.

^cCBT: cognitive behavioral therapy.

^dSM: self-monitoring.

^eBA: behavioral activation.

^fCR: cognitive restructuring.

^gAT: assertiveness training.

^hPS: problem-solving.