Table 1.
Distribution of α-thalassemia genotypes in Quanzhou region of Southeast China
| Genotypes | Cases | Frequency | Class |
|---|---|---|---|
| --SEA/αα | 1144 | 70.84% | Common |
| -α3.7/αα | 301 | 18.64% | Common |
| -α4.2/αα | 59 | 3.65% | Common |
| αQSα/αα | 25 | 1.55% | Common |
| αCSα/αα | 21 | 1.30% | Common |
| -α3.7/--SEA | 19 | 1.18% | Common |
| -α3.7/-α3.7 | 10 | 0.62% | Common |
| αWestmeadα/αα | 7 | 0.43% | Common |
| -α4.2/--SEA | 5 | 0.31% | Common |
| -α3.7/-α4.2 | 3 | 0.19% | Common |
| αCSα/--SEA | 2 | 0.12% | Common |
| αQSα/--SEA | 1 | 0.06% | Common |
| αCSα/-α3.7 | 1 | 0.06% | Common |
| αCSα/αCSα | 1 | 0.06% | Common |
| --THAI/αα | 5 | 0.31% | Rare |
| αIVS−II−55(T> G)α/αα | 2 | 0.12% | Rare |
| --FIL/αα | 2 | 0.12% | Rare |
| --THAI/-α3.7 | 1 | 0.06% | Rare |
| αCD30α/αα | 1 | 0.06% | Rare |
| αCD15α/αα | 1 | 0.06% | Rare |
| ααCD117/118/αα | 1 | 0.06% | Rare |
| αIVS−II−119(−G)(+CTCGGCCC), IVS−II−55(T> G)α /--SEA | 1 | 0.06% | Rare |
| αIVS−II−119(−G)(+CTCGGCCC), IVS−II−55(T> G)α /αα | 1 | 0.06% | Rare |
| αααanti3.7/αα* | 1 | 0.06% | Rare |
| Total | 1615 | 100.00% | / |
*:In this case, Hb G-Honolulu was also compounded