Fig. 2.

The 2-AG-Ps-PCL system provides sustained release. A Particle size, PDI and zeta potential of the nanoparticles (n = 3). B,C,D,E,F,G SEM micrographs of nanoparticle formulations (B) blank PCL (MW: 10 kDa), (C) 2-AG-PCL (MW: 10 kDa), (D) 2-AG-Ps-PCL (MW: 10 kDa), (E) blank PCL (MW: 45 kDa), (F) 2-AG-PCL (MW: 45 kDa), and (G) 2-AG-Ps-PCL (MW: 45 kDa). NPs were observed in the range of approximately 200–500 nm as globular particles with an electron lucent halo around the periphery (white arrows). Scale bar: 40 μm, ×2.500. H, i (h) Associated 2-AG (%) and (I) cumulative 2-AG release of nanoparticle formulations (n = 3, ±SD)