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. 2024 Oct 2;24:130. doi: 10.1186/s40644-024-00775-8

Table 1.

Patient clinical characteristics and histologic types

Parameters Benign (n = 399) Malignant (n = 1396) P value
Age, median (range, years) 50 (18–84) 56 (18–86)  < 0.001
Gender, n (%)  < 0.001
 Female 273 (68.4) 418 (29.9)
 Male 126 (31.6) 978 (70.1)
Laterality, n (%) 0.480
 Left 182 (45.6) 667 (47.8)
 Right 217 (54.4) 729 (52.2)
Lesion size, median (range, cm) 3.9 (0.9–19.3) 3.5 (0.9–13.9)  < 0.001
CT reported results  < 0.001
 Malignant 102 (25.6) 1146 (82.1)
 Equivocal 47 (11.8) 211 (15.1)
 Benign 250 (62.7) 39 (2.8)
Lesion subtype, n (%) -
 Clear cell RCC - 1191 (85.3)
 Papillary RCC - 51 (3.7)
 Chromophobe RCC - 78 (5.6)
 MiT Family translocation carcinomas - 32 (2.3)
 Other malignant renal tumor - 16 (1.1)
 Unclassified RCC - 28 (2.0)
 Angiomyolipoma 307 (76.9) -
 Oncocytoma 18 (4.5) -
 Cyst 55 (13.8) -
 Other benign renal tumor 19 (4.8) -

Other malignant renal tumors included 4 cases of multilocular cystic RCC, 4 cases of sarcomas, 3 cases of clear cell papillary RCC, 2 cases of well-differentiated neuroendocrine tumors, 1 case of succinate dehydrogenase deficient RCC, 1 case of collecting duct carcinoma, and 1 case of malignant perivascular epithelioid cell tumor. Other benign renal tumors included 6 cases of adult cystic nephroma, 4 cases of juxtaglomerular cell tumor, 3 cases of metanephric adenoma, 2 cases of papillary adenoma, 2 cases of inflammatory myofibroblastic tumors, 1 case of mixed epithelial and stromal tumor, and 1 case of schwannoma

RCC Renal cell carcinoma