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. Author manuscript; available in PMC: 2024 Oct 2.
Published in final edited form as: Nat Aging. 2024 Jun 28;4(9):1290–1307. doi: 10.1038/s43587-024-00662-8

Fig. 3 |. Gene-level biological pathway annotation and tissue-specific gene expression.

Fig. 3 |

a, Validation of the nine BAGs in GSEAs. GSEAs were performed using curated gene sets and Gene Ontology terms from the MSigDB database. b, Validation of the nine BAGs in gene property analyses. Gene property analyses evaluate tissue-specific gene expression for the nine BAG-related genes using the full SNP P value (two sided) distribution. Only significant gene sets are presented after adjusting for multiple comparisons using the Bonferroni correction; EGJ, esophagus gastroesophageal junction; FDVP, forebrain dorsal–ventral pattern; VLDL, very-low-density lipoprotein; CN, copy number; POR, Schmidt port targets in limb bud.