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. 2024 Sep 28;17:823–829. doi: 10.2147/IMCRJ.S483023

Table 1.

13 Cases of Vaccination-Associated Urticarial Vasculitis

Case Age Sex Past medical history Type of vaccination Number of vaccination Onset time Cutaneous symptoms Place of eruptions Systemic symptoms Laboratory data Treatment period Treatment for urticarial vasculitis
Misely L, et al2 21 Male None Bacillus Calmette-Guérin First 30 days after vaccination Urticarial eruption Upper limbs Fever and polyarthralgia Hyperleukocytosis and lowered C4 level 24 weeks None
Velasco-Tamariz V, et al3 6 Female None Serogroup B meningococcal First 7 days after vaccination Annular and arciform urticarial wheals Lower limbs None None 2 weeks Antihistamines
Hughes R, et al4 21 Female None Influenza Unknown 6 days after vaccination Urticarial plaques Trunk None None 2 weeks Antihistamines
Ono H, et al5 68 Male Diabetes mellitus, and hyperlipidemia COVID-19 Third 4 days after vaccination Edematous erythema Trunk and extremities Fever and polyarthralgia Hyperleukocytosis and elevated C-reactive protein 1 week Oral prednisone and antihistamines
Baraldi C, et al6 78 Female None COVID-19 First 7 days after vaccination Urticarial rash Extremities None None 4 weeks Oral prednisone
Nazzaro G, et al7 27 Female None COVID-19 First 10 days after vaccination Erythematous wheals Trunk and extremities None None 8 weeks Oral prednisone and antihistamines
Dash S, et al8 27 Male None COVID-19 Second 1 day after vaccination Urticarial plaques Trunk and extremities None Elevated C-reactive protein level 1 week Oral indomethacin and antihistamines
Daldoul M, et al9 73 Male Chronic urticaria COVID-19 Second 2 days after vaccination Purpuric and reticulated plaques Trunk and extremities None Hyperleukocytosis and elevated C-reactive protein level 1 week None
Larson V, et al10 35 Female None COVID-19 First 1 day after vaccination Erythematous and edematous plaques Trunk and extremities None Unknown Unknown Oral prednisone, dapsone, and antihistamines
Tihy H, et al11 73 Male None COVID-19 Second 21 days after vaccination Papules and urticarial plaques Trunk None Unknown Unknown Unknown
Holmes GA, et al12 86 Female None COVID-19 Second 5 days after vaccination Purpuric rash Face, trunk and extremities None None 2 weeks Oral prednisone and antihistamines
Imamura N, et al13 61 Male None COVID-19 First 14 days after vaccination Purpura and urticaria-like rash Extremities Fever, polyarthralgia, and swollen lymph nodes Pancytopenia, increase in ferritin and C-reactive protein level, and decrease in CH50, C3, and C4 levels More than 40 weeks Steroid pulse with tapered oral prednisone, and oral cyclosporine
Our case 67 Female None Influenza More than five times 3 days after vaccination Purpura and urticaria-like rash Trunk and extremities None Elevated C-reactive protein, D-dimer, and anticardiolipin antibody level 12 weeks Antihistamines