TABLE 1.
Demographic and clinical sample characteristics in the repetitive transcranial magnetic stimulation (rTMS) and intermittent theta-burst stimulation (iTBS) groups of patients with major depressiona
| Measure | 10 Hz rTMS group (N=144) | iTBS group (N=151) | ||
|---|---|---|---|---|
| N | % | N | % | |
| Female | 83 | 58 | 94 | 62 |
| Male | 61 | 42 | 57 | 38 |
| Mean | SD | Mean | SD | |
| Age (years) | 43.3 | 12.6 | 42.5 | 10.4 |
| Age at onset (years) | 20.8 | 11.2 | 20.9 | 11.3 |
| Baseline HAM-D score | 23.4 | 4.6 | 23.6 | 4.4 |
| Baseline QIDS-SR score | 17.4 | 3.8 | 16.7 | 4 |
| Clinical improvement (% change in HAM-D score) | 42.0 | 30.9 | 42.7 | 33.3 |
| Clinical improvement (% change in QIDS-SR score) | 37.1 | 30.2 | 36.9 | 37.4 |
| Depressive episode duration (months) | 24.6 | 30.4 | 21.3 | 25.9 |
| N | % | N | % | |
| Previous electroconvulsive therapy | 2 | 1.4 | 14 | 9.3 |
| Comorbid anxiety | 85 | 59.0 | 83 | 55.0 |
| Receiving psychotherapy during treatment | 59 | 41.0 | 65 | 43.0 |
| Receiving pharmacotherapy during treatment | 127 | 88.2 | 123 | 81.5 |
| Antidepressant | 120 | 83.3 | 115 | 76.2 |
| Benzodiazepine | 48 | 33.3 | 54 | 35.8 |
| Antipsychotic augmentation | 28 | 19.4 | 26 | 17.2 |
| Lithium augmentation | 5 | 3.5 | 3 | 2.0 |
| Anticonvulsant | 6 | 4.2 | 4 | 2.6 |
a
HAM-D=17-item Hamilton Rating Scale for Depression; QIDS-SR=16-item Quick Inventory of Depressive Symptomatology (self-rated).