Subgroups were defined as the modal subgroup assignment over the 1,000 training set replicates, which is used in the main text for Figs. 3–6. (a-d) Heatmaps show patterns of atypical connectivity in each subgroup across brain regions (rows) and functional networks (columns). Thresholded for significant atypical connectivity (two-sided Welch’s t-test, FDR < 0.05), evaluated in N = 69 ASD subjects in subgroup 1, N = 87 ASD subjects in subgroup 2, N = 67 ASD subjects in subgroup 3, N = 76 ASD subjects in subgroup 4, relative to N = 907 neurotypical controls.