Rotarod performance. Rotarod latencies were measured in male and female CBA/CaJ mice at 5, 16, and 24 months of age; 5 m (20, 10 males and 10 females), 16 m (20, 10 males and 10 females), 24 m (20, 10 males and 10 females). Data are shown as means ± SEM. Two-way ANOVA with Bonferroni’s multiple comparisons test was performed. m, months of age; M, male; F, female.