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. Author manuscript; available in PMC: 2024 Oct 2.
Published in final edited form as: Hear Res. 2022 Dec 27;428:108684. doi: 10.1016/j.heares.2022.108684

Fig. 2.

Fig. 2.

Wheel running activity. Total (A), light cycle (B), and dark cycle (C) wheel running activities were measured in male and female CBA/CaJ mice at 5, 16, and 24 months of age; 5 m (20, 10 males and 10 females), 16 m (16, 6 males and 10 females), 24 m (15, 7 males and 8 females). Data are shown as means ± SEM. Two-way ANOVA with Bonferroni’s multiple comparisons test was performed; C Dark cycle, Post hoc Bonferroni’s tests showed a significant sex difference for 5 m (*, P < 0.05, P = 0.0217), sex effect (F = 3.273, DF = 1, P = 0.0771), age effect (F = 21.92, DF = 2, P < 0.0001), interaction (F = 3.451, DF = 2, P = 0.0403). m, months of age; M, male; F, female; WR, wheel running; light cycle, from 7 am to 7 pm; dark cycle, from 7 pm to 7 am.